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Thursday, September 29, 2011

African Malaria Network Trust





Staff Profiles

  •  
    Prof Wen Kilama
    Managing Trustee
    Wen Kilama is a retired malaria researcher and Professor of Parasitology. He is the founder and first Managing Trustee of the African Malaria Network Trust (AMANET). Professor Kilama has steered AMANET since its founding as Africa Malaria Vaccine Testing Network (AMVTN) in 1995 to an organization that is leading Africa in researching, developing and eventual deployment of affordable malaria intervention tools. He is currently leading efforts in reforming AMANET. Being a Member of both AMANET and Multilateral Initiative on Malaria Boards, and the AMANET Scientific Coordinating Committee, he provides visionary and strategic guidance to both.
    Professor Kilama earned his doctorate in biology from the University of Notre Dame in 1970, and is a Chartered Member of the Alumni Academic Hall of Fame of St. Michael's College, Vermont, USA. He then returned to Tanzania where he founded and headed the Department of Parasitology and Medical Entomology, Muhimbili University of Health and Allied Sciences (then a faculty   of the University of Dar es salaam)  in 1970. Dubbed as the "Grand Old Man of African Malaria Research", he has to his credit over one hundred scholarly papers. Before founding AMANET, Prof Kilama founded and became first Director-General of the National Institute for Medical Research in Tanzania, a position he held for seventeen years.

    He is among other things a former Chairman of the Malaria Foundation International, Past President of the World Federation of Public Health Associations, and member of the WHO global Advisory Panel on Health Research. Professor Kilama is Honorary Fellow of the Royal Society of Tropical Medicine and Hygiene.

    He has served in various capacities on numerous committees and task forces for the World Health Organization, the World Bank, US agencies, and the European Commission among others. He is an exceptional advisor for malaria research capacity strengthening throughout Africa, as well as an expert source of knowledge and advice on issues pertaining to both health research ethics and sustainable development in malaria research.
  •  
    Prof James Oloo, MD, PhD
    Network Director
    As Network Director, Prof Oloo, deputizes the Managing Trustee, spearheads planning and implementation of AMANET programmes, projects, training, seminars, scholarships and fellowships, strategic planning and dissemination of network outputs to the various stakeholders. He promotes inter-agency relations between AMANET and its stakeholders and collaborators.
    Prior to joining AMANET, Prof. Oloo served at the WHO Africa Regional Office(WHO-AFRO) in Harare, Zimbabwe as the focal point in the planning and implementation of programmes and innovative strategies for strengthening health systems (traditional and community / Home based) for control and prevention of malaria and other priority diseases. Before joining WHO-AFRO, Prof Oloo was Associate Professor in the department of Epidemiology and Preventive Medicine, at the Faculty of Health Sciences, Moi University and, Director Kenya Medical Research Institute (KEMRI), Kisumu (1989 – 1999).
    Prof Oloo holds an MBChB degree and Masters of Medicine degree from the University of Nairobi. He also held additional fellowships on Tropical Medicine and on Clinical Epidemiology from Liverpool School of Tropical Medicine, UK and University of Newcastle, Australia respectively. He has authored and co- authored several publications on malaria, other communicable diseases and in public health.
  •  
    Dr Dawit Ejigu, MD, MSc
    Clinical Trials Coordinator
    As a Clinical Trials Coordinator Dr Ejigu coordinates all Clinical Trials sponsored by AMANET and ensures the trials are conducted in conformance with applicable international standards and local regulations. Together with Project Managers, Clinical Research Associates, clinical monitors and clinical trial site staff members, Dr Ejigu is responsible for planning, implementing, monitoring and evaluating clinical trials under AMANET sponsorship. He will also serve as interface between AMANET and key external contacts and collaborators including product developers, contract research organizations and research associates. Apart from coordination of clinical trial activities, he works towards maintaining the quality assurance programme in AMANET and coordinates external audits.

    Dr Ejigu obtained his Medical Doctorate degree from University of Gondar, Ethiopia in 2001 and graduated with Masters in Pharmacology from the Addis Ababa University (AAU), Ethiopia in 2005. He worked as Assistant Lecturer at Department of Pharmacology, University of Gondar immediately after his medical studies. He also worked as Assistant Professor of Pharmacology in the AAU, Faculty of Medicine.

    Dr Ejigu attended a one year fellowship organized by GSK-Bio/TDR in GlaxoSmithKline Biologicals, Belgium on tuberculosis vaccine development in 2007/2008 where he worked as Global Study Manager. Following his training at GSK-Bio he worked as Clinical Monitor for TDR. Dr Ejigu has also worked as Clinical Trial Associate and Project Manager for European Malaria Vaccine Initiative (EMVI)/European Vaccine Initiative (EVI).
  • Dr Noor is AMANET's Clinical Trials Coordinator and Project Coordinator (CTC) for the GMZ2 Consortium. As CTC he is responsible for the coordination of all AMANET sponsored clinical trials, and therefore the principal advisor to the Managing Trustee on all matters relating to clinical trials, including their planning, execution, monitoring and evaluation.
    In addition, he assists the Managing Trustee in conceptualizing, planning and execution of other AMANET projects such as training workshops, web-based learning in Health Research Ethics and Good Clinical Practice. As Project Coordinator, he is responsible for the overall coordination of the GMZ2 Consortium, an integrated project  involving seven north and south partners working to foster research capacity, networking and project management through phase I-IIb clinical trials of candidate malaria vaccine GMZ2
    He joined AMANET in 2007 as Projects and Sites Manager and oversaw the expansion of Afroimmunoassay (AIA) network activities in to the European Malaria Vaccine Development Association (EMVDA) Integrated Project where AMANET is a collaborating partner. Dr Noor continues to provide strategic leadership in this network.
    Previously he worked for four years with the Muhimbili University of Health Sciences-Harvard Research Collaboration as a research physician, and later as an Assistant to the Field Director for Muhimbili – Dar Es salaam City – Harvard School of Public Health (MDH) HIV/AIDS Care, Treatment and Programme. While at Harvard, he concurrently worked as a part-time Research Fellow with the Department of Nutrition Epidemiology, Harvard School of Public Health mainly focusing on Multivitamins and HIV/AIDS trials for people on highly active anti-retroviral therapy (HAART). Before that Dr Noor worked as a Registrar Medical Officer at Muhimbili National Hospital (2001-2003) in Tanzania.
    Dr Noor is an ACRP certified clinical research associate (CCRA, ACRP) with a Doctor of Medicine degree (University of Dar Es Salaam, Tanzania, 2001) and a Masters in Public Health (Quantitative Methods) from Harvard.

  • Dr Aceme Nyika, BSc, PhD, MPH
    Ethics Coordinator
    Dr Nyika joined AMANET in April 2007. As Ethics Coordinator, he is the focal person for the “Building Institutional Capacities in Health Research Ethics (HRE) in Africa” project funded by the Bill and Melinda Gates Foundation. He manages the HRE Project which aims at strengthening the ethical review process at African health research institutions, training health research investigators in HRE and promotion of African perspectives to Health Research Ethics through the creation and fostering of an electronic discussion forum, and encouragement of electronic discussion and debate on bioethics issues in Africa.
    Before joining AMANET, Dr Nyika was an Ethics Fellow with the Malaria Genomic Epidemiology Network (MalariaGEN) at the University of Oxford and at the University of KwaZulu-Natal (2006-2007) and before that he was Ethics Fellow with the Center for the AIDS Programme of Research in South Africa (CAPRISA) in 2005. Dr Nyika was a lecturer at the University of Zimbabwe (2000-2003) where he contributed to the development of an Ethics Committee at the University.
    Dr Nyika obtained his Bachelor of Science in Biosciences at the University of Zimbabwe in 1992, holds a PhD degree in Molecular Biology from the University of Florida, and Master of Public Health degree majoring in Health Research Ethics from the University of Pretoria.
  •  
    Mr Badru Amri, BCom, ACPA, ACCA
    Finance & Administration Manager
    Previous positions as Admin and Finance Officer with UNICEF Tanzania 2002 - 2003 and Chief Internal Auditor Habib Bank (Tz) 2000 – 2002), Finance and Administrative Manager for AMANET 2003 – present, Holder of Bachelor Commerce, University of Dar es Salaam 1994.








  •  
    Dr Brenda Okech, PhD
    GMZ2 Project Manager
    Dr Brenda Apio Okech is the GMZ2 Project Manager since January 2009. The new Integrated GMZ2 Project is funded by European-Developing Countries Clinical Trials Partnership (EDCTP) and comprises a consortium of seven international partners operating under four work packages. As GMZ2 Project Manager, Dr Okech works in collaboration with consortium work package leaders to ensure smooth and timely implementation of the project. Particularly, she will be responsible for developing and implementing innovative and up to date information sharing mechanisms within the consortium, generating monthly updates of project activities, facilitating south-south and north-south trainees and fellowship placements within networked institutions, and organizing GMZ2 Project Steering Committee meetings among other activities.
    Dr Okech brings with her extensive experience in different aspects of malaria vaccine trials. Prior to joining AMANET, she worked as a Senior Research Scientist at Med Biotech Laboratories (MBL) in Kampala, Uganda. At MBL, she was involved in preclinical malaria studies and also in preparations for future malaria vaccine clinical trials. She was also responsible for supervising graduate students and assisting the MBL Director in managing immunology projects.
    Dr Okech obtained her Bachelor of Science in Biochemistry from Makerere University, Uganda in 1995, subsequently joining Med Biotech Laboratories as a Research Associate 1996. Dr Okech holds a PhD in Immunology from the London School of Hygiene & Tropical Medicine (2000-2004). After her PhD, she returned to MBL until 2007 when she joined Glaxo Smith Kline (GSK) Laboratories in Belgium for a one-year WHO/GSK Fellow in management of malaria vaccine clinical research and development. She is currently a WHO Clinical Monitor and has provided consultancy in various missions.
  •  
    Mr Bonney Majila, BCom, MBA
    Accounts & Procurement Office (APO)
    As APO, Mr Majila assists the Finance and Administration Manager in executing AMANET projects particularly the Health Research Ethics (HRE) project funded by the Bill and Melinda Gates Foundation. He is responsible for monitoring project finances, procurements, operations, and ensuring that AMANET sub-grantees adhere to agreed financial and accounting procedures.
    Before joining AMANET, he worked as Finance and Administration Manager forPlan International-Kibaha Programme Unit, Tanzania (2006-2007) where he was responsible for projects funded from various international sources. Prior to this he had worked as Programme Accountant and Administrator for World Vision Tanzania (2001-2005).
    Mr. Majila obtained his Bachelor of Commerce and Management (Finance Major) at the University of Dar es salaam, Tanzania, in 2000. He also holds a Masters degree in Business Administration majoring in Finance and Banking from the Mzumbe University, Tanzania.
  • Leila Mfinanga 
    Ms Leila Mfinanga, BA
    Executive Assistant
    Ms Mfinanga is Executive Assistant to the Managing Trustee (MT). She assists MT with correspondence, literature search, preparation of publications, and presentations. She also provides secretarial services to MT, and to the Secretariat staff. Other duties include keeping records of management, Scientific Coordinating Committee (SCC) and Board of Trustees (BOT) meetings and other meetings; following up implementation of agreed decisions; makeing travel arrangements for Secretariat staff, meetings, workshops and conferences; and maintaining and updatings filing system and archiving for the Secretariat.

    Before joining AMANET, Ms Mfinanga worked as Administrative  Officer for the School of Public Health and Social Sciences at Muhimbili University of Health and Allied Sciences in Tanzania (2003 – 2007), and as a Research Fellow (2001 – 2003). She holds a Bachelor of Arts Degree (International Relations and Public administration, 2001) of the University of Dar es salaam.

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9 Malaria Surveillance [Read-Only].pdf 17 Aug 2011 06:27  by IHI Webmaster

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2 Zanzibar Malaria Control Program[1] [Compatibility Mode].pdf 17 Aug 2011 07:32  by IHI Webmaster

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Monitoring and evaluation tools to allow sustained elimination of malaria transmission 17 Aug 2011 06:39  by IHI Webmaster

 Full Title Monitoring and evaluation tools to allow sustained elimination of malaria transmission.  Short Title  Project Leader Gerry Killeen  Description As Tanzania makes progress in delivering malaria control measures to ...
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Phase III, Malaria Vaccine Test of RTS,S/AS01E 10 Sep 2011 02:26  by IHI Webmaster

... in infants and children, the efficacy of the RTS,S/AS01E candidate vaccine against malaria disease caused by P. falciparum infection, across diverse malaria transmission settings in Africa.  Short Title ...
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Population genetics of malaria vectors 17 Aug 2011 05:49  by IHI Webmaster

 Full TitlePopulation genetics of malaria vectors in mainland Tanzania and Zanzibar and potential for spread of insecticide resistance.  Short Title Population Genetics  Project Leader Deodutus Maliti  Description Very little ...
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Community Effectiveness of Intermittent Preventive Treatment delivered through the Expanded Programme of Immunisation for Malaria and Anaemia Control in Tanzanian Infants 16 May 2011 05:41  by IHI Webmaster

... Community Effectiveness of Intermittent Preventive Treatment delivered through the Expanded Programme of Immunisation for Malaria and Anaemia Control in Tanzanian Infants.  Short Title  Project Leader Hassan Mshinda  Description A controlled ...
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Zooprophylaxis as a malaria control strategy in Tanzania 18 Apr 2011 12:59  by IHI Webmaster

 Full Title Evaluating the potential of zooprophylaxis as a malaria control strategy in Tanzania: Do livestock influence malaria mosquito survival, reproduction and transmission potential?  Short Title Zooprophylaxis as a malaria ...
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CDC Activities in Tanzania

US President's Malaria Initiative

CDC supports malaria control efforts for the mainland National Malaria Control Programme and the Zanzibar Malaria Control Programme as part of the US President’s Malaria Initiative (PMI). Since 2005, this effort has produced phenomenal gains in access to malaria prevention and treatment interventions in Tanzania and across the Zanzibar Archipelago. For more information on PMI activities in Tanzania, see www.pmi.govExternal Web Site Icon.
A map of Tanzania
Tanzania

CDC/IHI Malaria Program in Tanzania

In addition to the agency’s key role in guiding and implementing PMI in the United Republic, CDC and the Ifakara Health Research and Development Centre (IHI)External Web Site Icon have collaborated on a series of cooperative agreements since 2000. The CDC/IHI Malaria Programme in Tanzania has emerged as a globally recognized leader in implementation and applied research to guide malaria control programs for both the mainland and Zanzibar Ministries of Health and Social Welfare and public health programs across the continent.
Between 2000 and 2006 the CDC/IHI Malaria Programme in Tanzania achieved the following milestones:
  • Completed the first programmatic implementation of artemisinin-containing combination therapy (ACT) in tropical Africa, delivering over a million treatment doses of highly effective malaria treatment in an isolated rural district for more than 4 years.
  • Established the complementary role of free and market-based strategies for delivering insecticide-treated mosquito nets (ITNs) for malaria prevention.
  • Characterized the public- and private-sector markets for malaria treatment and demonstrated how national policies can affect the equitable access to treatment for impoverished rural communities.
  • Documented the distribution of drug-resistant strains of malaria across rural Tanzania and the rest of Africa.
  • Established the relative contribution of diagnostically confirmed malaria among patients presenting to first-line health facilities and drug stores in rural Tanzania.
  • Completed the first national survey on quality of antimalarial drugs available in the retail sector and established the extent of distribution of artemisinin monotherapies in urban Dar es Salaam.
  • Contributed to a global model of malaria risk, coordinated by Oxford University.
  • Established best practices for achieving high adherence to complex 3-day treatment regimens with at least 2 ACTs.
  • Compared 3 possible regimens for the intermittent preventive treatment of malaria in pregnancy.
  • Established the impact of ACT and ITNs on nearly eliminating malaria transmission in the Zanzibar Archipelago.
  • Provided detailed implementation evidence for the roll-out of rapid diagnostic tests for malaria in rural Africa.
  • Demonstrated how interventions to improve the care of severely ill children could be effectively implemented in the context of the Integrated Management of Childhood Illness.
  • Monitored the costs and policy implications of delivering ACT as routine first-line treatment for malaria at district and national levels.
  • Elaborated the health-equity implications of delivering malaria treatment and prevention.


IMPACT Tz team members conducting a household survey in Rufiji District
IMPACT Tz team members conducting a household survey in Rufiji District, 2006.
Credit: S. Patrick Kachur, CDC
These activities were completed as part of the Interdisciplinary Monitoring Project for Antimalarial Combination Therapy in Tanzania (IMPACT-Tz), supported by CDC, the US Agency for International Development, and the Wellcome Trust. In addition to IHI, key partners included the Australian National University, the London School of Hygiene and Tropical Medicine, and the Swiss Tropical Institute.
Since the completion of IMPACT-Tz, the CDC/IHI Malaria Programme in Tanzania has continued to support the Malaria Control Programmes in both Ministries by providing:
  • Funding for in vivo and in vitro assays of antimalarial drug resistance.
  • Opportunities for Tanzanian scientists to train alongside US-based laboratorians.
  • Support for quality assurance of rapid diagnostic tests for malaria.
  • Technical guidance for the operational research component of mainland Tanzania’s Round 4 award from the Global Fund to Fight HIV/AIDS, Tuberculosis and Malaria (GFATM).
Beginning in 2009/2010 the CDC/IHI Malaria Programme will implement an evaluation of mainland Tanzania’s Round 7 award from GFATM to explore the impact of introducing rapid diagnostic tests for malaria and a highly subsidized ACT in the private retail sector. This will be done collaboratively with the ACT Consortium at the London School of Hygiene and Tropical Medicine, through a grant from the Bill and Melinda Gates Foundation. CDC and IHI are looking forward to future collaborative opportunities along this model.

For more information about the CDC/ IHI Malaria Programme in Tanzania, contact:

Elizeus Kahigwa, MD, PhD
Ifakara Health Research & Development Centre
PO Box 78373
Dar es Salaam, Tanzania
Tel: 255 222 774 714
Mobile: 255 744 481 965
Fax: 255 222 771 7143
E-mail: ekahigwa@ihrdc.or.tz / ekahigwa@yahoo.com

Peter D. McElroy, PhD, MPH
CDC Advisor to President's Malaria Initiative (PMI)
CDC-Tanzania
Tel: 255 22 212 1412 ext. 8474
Mobile: 255 (0)75 422 2247
E-mail: mcelroyp@tz.cdc.gov

S. Patrick Kachur, MD, MPH, FACPM
CDR, USPHS
Chief, Strategic and Applied Sciences Unit
Malaria Branch, Division of Parasitic Diseases
National Center for Zoonotic, Vector-Borne & Enteric Diseases
Coordinating Center for Infectious Diseases
Centers for Disease Control and Prevention
4770 Buford Highway, NE Mailstop F-22
Atlanta, Georgia 30341 USA
Tel: 1 770 488 3600
Fax: 1 770 488 4206
E-mail: spkachur@cdc.gov
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